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Dietary SupplementGluten FreeCirculationHeart/VesselsMen's HealthSignificant research supports the cardiovascular benefits of L-arginine in promoting vascular health and blood flow.* L-arginine enhances nitric oxide production in the arteries which in turn relaxes blood vessels and maintains healthy blood flow. Thorne's L-Arginine Plus with nutrients for added support combines sustained-release L-arginine with nutritional cofactors that enhance nitric oxide synthesis in the blood vessels (5-MTHF and ascorbic acid) in addition to antioxidants and botanicals that promote normal blood flow (R-lipoic acid green tea extract and resveratrol).*Thorne's L-Arginine is available for individuals who only want to supplement with L-arginine.L-arginine is a semi-essential amino acid that is involved in multiple areas of human physiology and metabolism.* It has a significant effect on endocrine function and helps regulate the release of neurotransmitter chemicals insulin glucagon (which has the opposite effect of insulin; i.e. it raises blood sugar) and growth hormone.* However one of L-arginine's most compelling contributions to human physiology is its role as a biological precursor of nitric oxide.* The lining of the arteries (the vascular endothelium) creates nitric oxide from L-arginine resulting primarily in the relaxation of the blood vessels.* This process is important to maintaining good vascular health heart health reproductive health and protection against oxidative damage.*Maintaining the healthy vascular endothelium function depends on an adequate supply of L-arginine being available to these cells.* Without adequate L-arginine – and the subsequent production of nitric oxide – available to the vascular endothelium arteries don't optimally dilate which results in less than optimal blood flow to the organs and extremities.*