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NSF Contents CertifiedDye Free Gluten Free VeganMTX Advanced Support® is a methylated folate and vitamin B12 supplement designed to provide nutrient support during methotrexate therapy.Formulated by Rheumatologists to support healthy folate levels.High-dose folate supplementation can "mask" an underlying B12 deficiency therefore it is recommended to take vitamin B12 along with folate. Independently content-certified by NSF® International.