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Improved Enteric CoatingDietary SupplementSupports Joint Comfort Function and MobilitySource Naturals® SAMe is a stable bioavailable form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed for consistent quality and optimal bioactivity. SAMe is present in every living cell in the body and plays an important part in many critical cellular functions. A number of clinical studies have demonstrated that SAMe supplementation supports joint comfort function and mobility in the spine hips and knees. Preliminary research suggests that SAMe may work by supporting the production of proteoglycans which are important components of cartilage. Numerous clinical studies have also demonstrated that SAMe can help support a positive outlook. It is able to cross the blood-brain barrier where it is thought to affect the syn- thesis of neurotransmitters and to help main- tain normal membrane fluidity. SAMe works together with the B-vitamins in particular folic acid making it important to obtain ad- equate amounts of the B-vitamin complex from diet and supplements. SAMe plays a key role in transmethylation a vital type of chemical reaction that affects the synthesis activation and metabolism of vari- ous biological molecules. Compounds that require this reaction include phospholipids which are fundamental for all cell membrane functions and for cell to cell communication.