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Dietary SupplementHelps Support The Cardiovascular SystemSuitable For VegetariansSource Naturals Homocysteine Defense™ is an excellent formula that may provide support to the cardiovascular system. Trimethylglycine (TMG) vitamins B-6 and B-12 and folic acid may help in the conversion of homocysteine to other substances including methionine thus preventing an unwanted build-up of homocysteine.