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Brain SupportBioavailable Source of CholineA Dietary SupplementVegetarian/Vegan How it works: Alpha GPC is a physiological precursor to acetyl-choline a neurotransmitter that is involved in memory and other cognitive functions. Alpha GPC is more bioavailable than other forms of choline and is known to cross the blood-brain barrier. In the brain and other neural tissues alpha GPC becomes a constituent of cell membranes. Scientific research suggests that supplementation with alpha GPC can support the brain's synthesis of acetyl-choline. In this way it helps to promote normal brain function and motivation.