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Supports Nervous System and Joint HealthStabilized SAMe Smaller TabletNo Enteric Coating NeededA Dietary SupplementHow it Works: SAMe (S-adenosylmethionine) a compound native to the body is a critical component of many biochemical reactions including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to alleviate transient normal aches and pains resulting from overexertion or stress. In addition because SAMe is also necessary for the synthesis of neurotransmitters it plays an important role in the maintenance of a positive mood.